A escritora, poeta e artista plástica Jânia Souza vai lançar mais dois livros de sua autoria durante live promovida pela União Brasileira de Escritores (UBE/RN). Será nesta quarta (26) às 19h no canal de youtube da entidade, mediado pela escritora e professora Carla Alves.
PIONEIRAS traça a trajetória de três mulheres potiguares precursoras na luta feminina por direitos civis e políticos na América Latina em uma sociedade comandada por homens e por machistas. São elas, Nísia Floresta, Alzira Soriano e Celina Guimarães.
“Elas são mulheres ícones que precisam ser resgatadas no coração das novas gerações. Além disso, seus valorosos feitos devem ser reconhecidos e aplaudidos pela humanidade”, enfatizou Jânia.
“Pioneiras” conta com apresentação da feminista Joluzia Batista Jô Batista, orelha da poeta e escritora Rizolete Fernandes. tem quarta capa da poeta e escritora Anchella Monte, projeto editorial e capa de Bruno Obos e sai pela Editora B3S.
O livro recebeu a terceira colocação no Prêmio de Literatura Nísia Floresta da Fundação José Augusto, na categoria Vozes Femininas.
Na última sexta-feira (21), Jânia Souza participou de live com Sônia Miquelin, presidente da Associazione Culturale Internacionale Mandala, italiana, para lançar o livro Pioneiras.
O Jumentinho Abel
O outro livro traz de volta o talento de escritora de livros infantis com a fábula “O Jumentinho Abel”, que trata do relacionamento entre professor e aluno valorizando a importância dos ensinamentos para o crescimento saudável e ajustado ao indivíduo e ao coletivo da criançada.
O livro recebeu o Prêmio de Literatura Infantil Carolina Wanderley. E assim como a obra “Pioneiras”, foi contemplado em Edital da FJA Lei Aldir Blanc RN.
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BPC 157 is a synthetic peptide that has attracted attention for its potential to
accelerate tissue repair and reduce inflammation. The molecule was originally discovered as
part of the human gastric mucosal protective
system and is sometimes referred to as “Body Protective Compound.”
In research settings, BPC 157 has shown promising results in animal studies where it appears to help heal tendons, ligaments, muscles,
nerves, and even gut tissue more quickly than would normally be expected.
Is this a supplement I should be taking to improve my healing?
The short answer is that while the pre‑clinical data are encouraging, there is
currently no regulatory approval for BPC 157 in humans, and it has not been tested in large randomized clinical trials.
Because of this lack of robust evidence, health authorities do not recommend its use as a standard therapeutic or supplement for injury recovery.
How does BPC 157 work?
In laboratory models, the peptide is thought to
modulate several growth factor pathways, such as vascular endothelial growth factor and fibroblast growth factor, which play key roles in angiogenesis and collagen synthesis.
It may also influence nitric oxide production, helping to improve blood flow to damaged tissues.
Additionally, some studies suggest that BPC 157 can reduce oxidative stress and suppress pro‑inflammatory cytokines, thereby creating a more favorable environment for healing.
What are the practical considerations if I decide to purchase
it? The product is typically sold as a powder or vial for reconstitution with sterile water.
Because it is not regulated by major health agencies, quality control varies widely
between suppliers. You should verify that the seller provides
detailed specifications, including purity grades and certificates of analysis
from third‑party testing laboratories. Look for vendors that list their batch numbers and provide traceability records.
Dosage protocols reported in animal studies range from 10 to 50
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Sermorelin is a synthetic peptide that mimics the natural growth hormone releasing hormone (GHRH) produced
by the hypothalamus. By stimulating the pituitary gland to release more growth hormone, it offers therapeutic benefits for conditions
such as growth hormone deficiency, aging-related declines in anabolic activity, and certain endocrine disorders.
Although many patients experience improvements in energy levels,
muscle mass, and overall well‑being, there are concerns about potential side effects that could arise from prolonged exposure to elevated
growth hormone levels, particularly the possibility of increasing cancer risk.
Sermorelin gh-related side effects Effects:
Is There a Cancer Risk?
Growth hormone (GH) and its downstream mediator insulin‑like growth
factor 1 (IGF‑1) play central roles in cellular proliferation, differentiation, and survival.
Because many tumors rely on these pathways for growth and resistance to apoptosis,
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The data from clinical trials and observational
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hormone replacement over many years. Importantly, these
findings are largely derived from data on recombinant human growth hormone (rhGH)
rather than sermorelin itself. Sermorelin is considered a more physiologic
stimulator because it triggers endogenous GH release rather than supplying exogenous hormone directly; however, the downstream signaling pathways—IGF‑1 production, mitogen‑activated protein kinase
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The current consensus among endocrinologists is that sermorelin therapy should be carefully monitored in patients with a personal or family history of cancer, especially those who have undergone treatment for hormone‑sensitive
tumors. Regular imaging studies, thyroid function tests,
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Introduction to Sermorelin Therapy
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The primary indications for sermorelin therapy include:
Growth hormone deficiency in children and adults, confirmed by dynamic testing.
Reproductive disorders such as hypogonadism where
GH levels are low.
Age‑related decline in anabolic activity leading to sarcopenia or frailty.
Certain endocrine conditions, like hypopituitarism or pituitary adenoma sequelae.
Patients often report subjective improvements within weeks of therapy:
enhanced sleep quality, increased energy, better mood, and improved skin elasticity.
Objective measures such as lean body mass gain, decreased visceral fat, and improved insulin sensitivity
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Understanding Sermorelin and its Uses
The mechanism of action for sermorelin is rooted in its structural similarity to endogenous GHRH.
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cyclase and increasing cyclic AMP production. This cascade triggers GH
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Because sermorelin’s effect is pulsatile—mimicking the natural circadian rhythm of
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In addition to its endocrine benefits, sermorelin has been explored for use in regenerative medicine.
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Key considerations when initiating sermorelin therapy include:
Baseline evaluation of growth hormone axis: serum GH peak after stimulation test, IGF‑1 levels, and thyroid function.
Screening for contraindications: active malignancy, uncontrolled diabetes,
or severe liver disease.
Monitoring during treatment: periodic measurement of IGF‑1 to avoid supraphysiologic exposure, assessment
of metabolic parameters (glucose tolerance, lipid profile), and vigilance for signs of fluid retention or edema.
Patients should be counseled about the possibility of mild injection site reactions—pain, redness, or swelling—which typically resolve within a day.
In rare cases, allergic reactions may occur; any sign of anaphylaxis warrants immediate medical attention.
In summary, sermorelin offers a physiologic approach to restoring growth hormone activity in patients with
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